The rapid development and increasing availability of high-resolution satellite (HRS) images provides increased opportunities to monitor large scale land cover. However, inefficiency and excessive independence on expert knowledge limits the usage of HRS images on a large scale. As a knowledge organization and representation method, ontology can assist in improving the efficiency of automatic or semi-automatic land cover information extraction, especially for HRS images. This paper presents an ontology-based framework that was used to model the land cover extraction knowledge and interpret HRS remote sensing images at the regional level. The land cover ontology structure is explicitly defined, accounting for the spectral, textural, and shape features, and allowing for the automatic interpretation of the extracted results. With the help of regional prototypes for land cover class stored in Web Ontology Language (OWL) file, automated land cover extraction of the study area is then attempted. Experiments are conducted using ZY-3 (Ziyuan-3) imagery, which were acquired for the Jiangxia District, Wuhan, China, in the summers of 2012 and 2013.The experimental method provided good land cover extraction results as the overall accuracy reached 65.07%. Especially for bare surfaces, highways, ponds, and lakes, whose producer and user accuracies were both higher than 75%. The results highlight the capability of the ontology-based method to automatically extract land cover using ZY-3 HRS images